There are a number of programs used by sponsors for proposal submission. The program guidelines for your proposal should designate the appropriate method of submission for your proposal. A few of the most common submission systems are listed below.
Cayuse 424 is an electronic research administration system that serves as a proposal development tool and submission portal to Grants.gov. If the proposal is required to be submitted through Grants.gov, most likely Cayuse 424 can be used instead. Cayuse 424 is a convenient, user-friendly interface that provides auto-filling of university and faculty profiles, and interactive error checking as the proposal is developed.
Grants.gov is an E-Government initiative operating under the governance of the Office of Management and Budget. Under the President's Management Agenda, the office was chartered to deliver a system that provides a centralized location for grant seekers to find and apply for federal funding opportunities. Today, the Grants.gov system houses information on over 1,000 grant programs and vets grant applications for 26 federal grant-making agencies.
Fastlane.nsf.gov and Research.gov
Fastlane and research.gov are the National Science Foundation (NSF) online websites through which they conduct their relationship to researchers and potential researchers, reviewers, and research administrators and their organizations.
eRA Commons is an online interface for the U.S. Department of Health & Human Services where signing officials, principal investigators, trainees and post-docs at institutions/organizations the tools necessary for electronic processing of research grants.